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African countries like Uganda and South Africa are rewriting the rules of emergency response. The rest of the world must follow – or fall behind.

As global health faces rising threats from pandemics, climate change, and conflict, African countries like Uganda and South Africa are offering critical lessons by integrating immunisation into broader emergency preparedness systems. Immunisation must be seen not merely as a tool to prevent disease, but as foundational infrastructure for pandemic preparedness and response (PPR). With trusted community networks, robust cold chain logistics, and real-time data systems, immunisation programmes are uniquely positioned to serve as early warning and rapid response mechanisms.

Uganda and South Africa exemplify this shift. Uganda leveraged its immunisation system during COVID-19 to enhance surveillance, contact tracing, and vaccine rollout—proving the value of integrating health security with routine services. South Africa adopted a whole-of-government approach, aligning its vaccination efforts with disaster management strategies and digital health platforms. These examples show that when countries treat immunisation as core public infrastructure, they build more resilient and responsive health systems.

Yet global frameworks still largely treat immunisation as a siloed vertical rather than a pillar of health security. As the World Health Assembly prepares to discuss the Pandemic Accord, there’s a risk of missing a pivotal opportunity to embed vaccines in the heart of preparedness planning. Delivering on the WHO’s Immunisation Agenda 2030 requires political will, integrated financing, and community leadership. Africa is showing the way—now the world must follow.

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Submitted by DavidLM on